The round of 16 lineup was confirmed on Thursday with PSV Eindhoven to meet Valencia CF, Manchester United FC to play Athletic Club and FC Twente to take on FC Schalke 04.
Arsene Wenger cut a distraught figure after his Arsenal side were humiliated 4-0 by AC Milan in the UEFA Champions League second round, first leg at the San Siro on Wednesday.
LIVERPOOL, ENGLAND - AUGUST 27: Martin Skrtel of Liverpool celebrates scoring his side's second goal during the Barclays Premier League match between Liverpool and Bolton Wanderers at Anfield on August 27, 2011 in Liverpool, England. (Photo by Clive Brunskill/Getty Images)